Keywords: ELMO1 (CED-12) and DOCK2 (CED-5) ternary complex in apoptosis.jpg en A A simple graphical representation of the protein domains for DOCK2 mammalian homolog to CED-5 and ELMO1 mammalian homolog for CED-12 On DOCK2/CED-5 the SH3-domain that binds to ELMO1/CED-12 is shown as a blue rectangle On ELMO1 Proline-Rich regions are in light-blue These indicate the regions in which ELMO1/CED-12 and DOCK2/CED-5 interact when forming a complex B A crystalline 3D-representation of the heterodimer structure between DOCK2/CED-5 and ELMO1/CED-12 On the right is the same crystalline structure rotated 90° 2012-02-13 http //www ncbi nlm nih gov/pubmed/22331897 Kyoko Hanawa-Suetsugu Mutsuko Kukimoto-Niino Chiemi Mishima-Tsumagari Ryogo Akasaka Noboru Ohsawa Shun-ichi Sekine Takuhiro Ito Naoya Tochio Seizo Koshiba Takanori Kigawa Takaho Terada Mikako Shirouzu Akihiko Nishikimi Takehito Uruno Tomoya Katakai Tatsuo Kinashi Daisuke Kohda Yoshinori Fukui and Shigeyuki Yokoyamaa other versions cc-zero Apoptosis SH3-domain Uploaded with UploadWizard |