Keywords: Monakow atlas.JPG The course of degenerated pyramidal tract fibres revealed by Marchi degeneration marked red points in the transverse sections b c and d Reproduced from Monakow 22 p 722 figs 171 “174 At the time this was the typical technique for establishing the connectivity of the motor and sensory pathway Brain sections from a patient who suffered from a haemorrhagic insult exitus six months later a The focus of the bleeding is indicated in black at upper midbrain level A massive interruption of descending fibres in the capsula interna entering the peduncle quasi-horizontal section led to their anterograde degeneration as viewed with the Marchi procedure b Transverse section at the midbrain level shows the degenerated fibres in the middle segment of the peduncle c At the pontine level descending degenerating fibres in a crescent-shaped order between islands of pontine neurons neurons not visible with the Marchi staining d Pyramid totally filled with degenerated fibres directed to the spinal cord C von Monakow Gehirnpathologie A Hölder Vienna 1897 1897 C von Monakow PD-Old Neuroanatomy Constantin von Monakow Spinal cord |