Keywords: Nuclear receptor action.png Created myself using CambridgeSoft BioDraw Boghog2 10 14 9 June 2007 UTC Mechanism nuclear receptor action This figure depicts the mechanism of a class I nuclear receptor NR which in the absence of ligand is located in the cytosol Hormone binding triggers dissociation of heat shock proteins HSP dimerization and translocation to the nucleus where it binds to a specific sequence of DNA known as a hormone response element HRE The nuclear receptor DNA complex in turn recruits other proteins that are responsible for translation of downstream DNA into RNA and eventually protein which results in a change in cell function Made by Boghog2 2007-06 Boghog2 Acción de receptores nucleares I png en En Wikipedia Boghog2 Genetic diagrams Systems biology Signal transduction |