MAKE A MEME
View Large Image
| View Original: | Type ii nuclear receptor action.png (2999x2249) | |||
| Download: | Original | Medium | Small | Thumb |
| Courtesy of: | commons.wikimedia.org | More Like This | ||
| Keywords: Type ii nuclear receptor action.png en Created myself using CambridgeSoft BioDraw Mechanism nuclear receptor action This figure depicts the mechanism of a class II nuclear receptor NR which regardless of ligand binding status is located in the nucleus bound to DNA For the purpose of illustration the nuclear receptor shown here is the thyroid hormone receptor TR heterodimerized to the RXR In the absence of ligand the TR is bound to corepressor protein Ligand binding to TR causes a dissociation of corepressor and recruitment of coactivator protein which in turn recruit additional proteins such as RNA polymerase that are responsible for transcription of downstream DNA into RNA and eventually protein which results in a change in cell function Own Boghog2 2008-11-30 Acción de receptores nucleares II png Cell diagrams Systems biology Signal transduction | ||||
