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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.
A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.
c-Myc and Max transcription factors bound to DNA. 3D illustration. Atoms shown as spheres with conventional color coding.
Abstract geometric shape
3D cartoon and Gaussian surface models. PDB 2aai, white background.
DNA A-T Pair
Tafamidis is a medication used to delay loss of peripheral nerve function in adults with familial amyloid polyneuropathy. 3d illustration
Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus
Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.
A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.
Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.
Abstract geometric shape
3D cartoon and Gaussian surface models, PDB 3hg3, white background
Model of human Insulin, a hormone to regulate carbohydrate and fat metabolism
Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
Multi-colored connected spheres building a molecular structure.
PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.
A model of a molecule of arginine, an amino acid. Amino acids are the building blocks of proteins and have many functions in metabolism. In particular, Arginine has an important function in the immune system, wound healing and cell division.
Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.
Spherical molecule render. The model is isolated on white and could be easily extracted as well as used with the background.
3D cartoon and Gaussian surface models, chain id color scheme, PDB 5y0m, white background
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Beta-alanine or β-Alanine molecule. It is naturally occurring beta amino acid. Molecular model. 3D rendering. Illustration
Render of molecule in hi-key
Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
A ball and stick model of a molecule of Human Glucagon, a hormone produced in the pancreas and used by the body to raise levels of glucose in the blood. Glucagon worksin the opposite manner to Insulin, which lowers levels of glucose in the blood - together they work to keep glucose levels stable.
Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.
Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, based on the chemical structure available in public space from U.S. National Library of Medicine, which was professionally checked. Color symbols - green=carbon, red=oxygen, blue=nitrogen, white=hydrogen, purple=phosphorus
3D cartoon and Gaussian surface models, chain id color scheme, PDB 4ci9, white background
molecular model of Sovaldi (generic name: Sofosbuvir), the most popular drug to treat hepatitis C infection
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Equilateral pentagon.SVG
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