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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.
A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.
3D cartoon and Gaussian surface models, PDB 6vg8, white background
Abstract geometric shape
c-Myc and Max transcription factors bound to DNA. 3D illustration. Atoms shown as spheres with conventional color coding.
DNA A-T Pair
3D rendering of biotinylated antibody, an engineered protein designed to bind to specific molecules. Biotin allows researchers to easily track and manipulate these antibodies.
Fictitious molecule model inside red and blue pill isolated on white.
Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.
A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.
3D cartoon and Gaussian surface models. PDB 2aai, white background.
Abstract geometric shape
Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.
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Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
Medical Laboratory Research Background
PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.
A ball and stick model of a molecule of gamma-Cyclodextrin. Composed of eight glucose sugar molecules bound into a ring structure, cyclodextrins are easily made from simple starch. The large ring can bind smaller molecules within it, making Cylodextrins useful in drug-delivery applications and also to clean up toxins (such as heavy metals) in the environment. Currently, gamma-Cyclodextrin is being considered as a structure which can bind to and hold carbon dioxide gas for carbon capture and storage as a way to manage the effect of excess carbon dioxide on the climate.
3D cartoon and Gaussian surface models, PDB 3hg3, white background
Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus
Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.
Amino Acid Lysine
Abstract Pink And Green Knot
Spherical molecule render. The model is isolated on white and could be easily extracted as well as used with the background.
Immunotherapy of Alzheimer's disease: Monoclonal antibody (light blue) bound to an amyloid beta peptide (orange), that is aggregated to amyloid beta fibrils, which build up amyloid plaques.
A ball and stick model of one of the proteins which form the fibres of spider's silk.
3D cartoon and Gaussian surface models, chain id color scheme, PDB 5y0m, white background
Colorful Molecules Background
Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.
Molecular model of Adenosine triphosphate, or Adenosine-5'-triphosphate (ATP)
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