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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.
A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.
3D cartoon and Gaussian surface models, PDB 1j7n, chain id color scheme, white background
Liquid bubbles up Fluid Twirl
Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.
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Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration
A molecule of sucrose, showing thermal ellipsoids.
Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.
A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.
3D cartoon and Gaussian surface models, chain id color scheme, PDB 5y0m, white background
Liquid bubbles up Fluid Twirl
Botulinum toxin neurotoxic protein, 3D rendering. Produced by Clostridium botulinum. Cosmetically used to treat wrinkles.
DNA A-T Pair
Cholera toxin, molecular model. Cholera toxin (choleragen) is a protein complex secreted by the bacterium Vibrio cholerae, that causes the disease cholera. It is made up of a wedge-shaped A subunit (right part of illustration) and five B subunits (left part of illustration) that form a ring which binds to the intestinal lining. In its most severe forms, cholera is one of the most rapidly fatal illnesses known.
Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus
PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.
A ball and stick model of Ethyl Eicosapentaenoic Acid or E-EPA. It is an omega-3 polyunsaturated fatty acid.
3D cartoon and Gaussian surface models. PDB 3kqg, chain id color scheme, white background.
Colorful Molecules Background
Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.
Maltose or maltobiose or malt sugar is a disaccharide formed from two units of glucose joined with an alpha bond. 3d illustration
Abstract Pink And Green Knot
A ball and stick model of a molecule of Human Glucagon, a hormone produced in the pancreas and used by the body to raise levels of glucose in the blood. Glucagon worksin the opposite manner to Insulin, which lowers levels of glucose in the blood - together they work to keep glucose levels stable.
3D cartoon and Gaussian surface models, chain id color scheme, PDB 4ci9, white background
3D Illustration of Vitamin C Molecule
Taq polymerase (Thermus aquaticus polymerase) enzyme bound to DNA, 3D rendering. Protein used in PCR (polymerase chain reaction).
Molecular model of lactose, a disaccharide sugar in milk.
Free Images: "bestof:PDB 1o2d EBI.jpg Multi-domain proteins alpha and beta Dehydroquinate synthase-like Dehydroquinate synthase-like Iron-containing alcohol dehydrogenase Alcohol"
Reaction catalyzed by 3-dehydroquinate synthase.svg
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