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PKM2 plays key roles in reprogramming cancer cells from energy production to growth (Warburg Effect). The dimeric form of the enzyme is not only less active in glycolysis but can also move into the nucleus to promote the transcription of other cancer-causing genes. A substrate analogon (red) is bound to the active site. PKM2 is a target for anti-cancer therapies. PDB entry: 6WP3.

A ball-and-stick molecular model of the hormone Orexin, also known as Hypocretin. Orexin is involved in the regulation of the sleep/wake cycle and it stimulates apetite, wakefulness and energy expenditure. It has been linked with Alzheimer's disease. Isolated on white.

Tryptophan or Trp is an alpha-amino acid that is used in the biosynthesis of proteins, 3d illustration

Indoleamine 2,3 dioxygenase 1 (IDO1) protein. Tryptophan catabolic enzyme of the kynurenine pathway. 3D illustration.

Rendered coronavirus/2019-nCoV single-stranded RNA, built from experimentally determined Ebola virus crystal structure. Color symbols - bluewhite=carbon, pink=oxygen, lightblue=nitrogen, white=hydrogen, lavender=phosphorus

3D cartoon and Gaussian surface models, PDB 3hg3, white background

A molecule of sucrose, showing thermal ellipsoids.

PETase (left) degrades polyethylene terephtalate (PET) into monohydroxyethyl terephthalate (MHET) and MHETase degrades MHET ethylene glycol (EG) and terephthalic acid (TPA). The substrates in the binding sites are depicted in red.

A space-filling molecular model of collagen, a fibrous protein that provides structural support in animals. It has a distinctive triple helix structure. Isolated on black.

Dopamine chemical molecule. It plays a role as a “reward center” 3d rendering

Molecular model of lactose, a disaccharide sugar in milk.

Glucose-6-phosphate dehydrogenase (G6PD) protein. Enzyme of the pentose phosphate pathway that generates co-enzyme NADPH. 3D illustration.

Colorful Molecules Background

3D cartoon and Gaussian surface models, chain id color scheme, PDB 8d45, white background

Avibactam is a diazobicyclooctane inhibitor of gram-negative and gram-positive bacteria. Avibactam (red) inhibits the bacterial enzyme beta-lactamase (blue) of Clostridioides difficile.

A ball and stick + ribbons model of HIV protease - an enzyme that is the target of much AIDS and HIV research.

Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration

Camostat drug molecule. Serine protease inhibitor, investigated for treatment of Covid-19. 3D rendering. Atoms are represented as spheres with convent

Caffeine Molecule with clipping path

3D cartoon and Gaussian surface models, PDB 1yf4, white background

Chemical science background

Beta-alanine or β-Alanine molecule. It is naturally occurring beta amino acid. Molecular model. 3D rendering. Illustration

A model of a molecule of arginine, an amino acid. Amino acids are the building blocks of proteins and have many functions in metabolism. In particular, Arginine has an important function in the immune system, wound healing and cell division.

Remdesivir is a broad-spectrum antiviral medication, it is a specific treatment for COVID-19. 3d illustration

molecular model of Sovaldi (generic name: Sofosbuvir), the most popular drug to treat hepatitis C infection

D-aspartic acid (D-aspartate) amino acid molecule. 3D rendering. Atoms are represented as spheres with conventional color coding.

Rendered Remdesivir molecule in 3D, an experimental drug from Gilead, used to cure the first case of 2019-nCoV in the United States (for a patient at Seattle, Washington). The model showed accurate atom connection and stereochemistry, which was professionally checked. Color symbols - light blue=carbon, red=oxygen, blue=nitrogen, white=hydrogen, green=phosphorus

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Symplocamide A.svg

Phenylmethanesulfonyl fluoride 200.svg

4-(2-aminoethyl)benzene-1-sulfonyl fluoride 200.svg

Drometrizole 200.svg

Drometrizole 100.svg

Adherens Junctions structural proteins-LangNeutral.svg

Parecoxib 200.svg

6,6'-methylenebis(2-(tert-butyl)-4-methylphenol) 100.svg

Fort Sumter Flag.svg

Portret van Jan van Huysum Rijksmuseum SK-A-5008.jpeg.jpg

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